abstract：:Recently, a salivary gland transcriptome study demonstrated that the transcripts of a putative cystatin gene (SeqID AAEL013287; Aacystatins) from Aedes aegypti were increased in DENV2-infected mosquitoes and that silencing of the Aacystatin gene resulted in an increase in DENV titres. In this work, Aacystatin was bioc...

journal_title：International journal of biological macromolecules

authors： Oliveira FAA,Buri MV,Rodriguez BL,Costa-da-Silva AL,Araújo HRC,Capurro ML,Lu S,Tanaka AS

更新日期：2020-03-01 00:00:00

abstract：:Breast cancer endocrine resistance prevents unleashing full capabilities of Tamoxifen (TMX), besides TMX off-target side effects on healthy tissue. In this study, we engineered TMX nanocomposite via co-loading it on alginate-based silver nanoparticles and embedding within folic acid-polyethylene glycol surface conjuga...

journal_title：International journal of biological macromolecules

authors： Ibrahim OM,El-Deeb NM,Abbas H,Elmasry SM,El-Aassar MR

更新日期：2020-03-01 00:00:00

abstract：:The aim of this study was to develop a novel approach allowing simultaneous enrichment as well as specific and fast detection of Escherichia coli O157:H7 by indirect ELISA using optimized support membrane based on chitosan (CHI), cellulose nanocrystals (CNCs), and glycerol (GLY). Therefore, combining the step of the c...

journal_title：International journal of biological macromolecules

authors： Baraketi A,D'Auria S,Shankar S,Fraschini C,Salmieri S,Menissier J,Lacroix M

更新日期：2020-03-01 00:00:00

abstract：:A gene encoding a halohydrin dehalogenase from Pseudomonas pohangensis (PpHHDH) was identified, synthesized and expressed in Escherichia coli. Subsequently, we used protein engineering to enhance the enzyme's enantioselectivity. We created two enantiocomplementary HHDH mutants, N160L and Q159L, which exhibited higher ...

journal_title：International journal of biological macromolecules

authors： Xue F,Yu X,Shang Y,Peng C,Zhang L,Xu Q,Li A

更新日期：2020-03-01 00:00:00

abstract：:Impacts of hot water extraction (HWE), pressurized water extraction (PWE), high-speed shearing homogenization extraction, microwave assisted extraction (MAE), ultrasound assisted extraction (UAE), ultrasound assisted enzymatic extraction, and ultrasound-microwave assisted extraction (UMAE) on physicochemical character...

journal_title：International journal of biological macromolecules

authors： Fu Y,Li F,Ding Y,Li HY,Xiang XR,Ye Q,Zhang J,Zhao L,Qin W,Gan RY,Wu DT

更新日期：2020-03-01 00:00:00

abstract：:We have earlier in silico designed the 3-dimensional structure of a protein enriched with branched chain amino acids (BCAA, 56.4%), having only α-helical coiled-coil structure. Here, homology modeling was used to improve the in silico designed protein model. The secondary and tertiary structures of improved protein mo...

journal_title：International journal of biological macromolecules

authors： L S,Vasu P

更新日期：2020-03-01 00:00:00

abstract：:A novel composite hydrogel was prepared as a dual drug delivery carrier. Poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) microparticles were prepared to encapsulate simultaneously ketoprofen and mupirocin, as hydrophobic drug models. These microparticles were embedded in a physically crosslinked hydrogel of κ-carragee...

journal_title：International journal of biological macromolecules

authors： Pettinelli N,Rodríguez-Llamazares S,Farrag Y,Bouza R,Barral L,Feijoo-Bandín S,Lago F

更新日期：2020-03-01 00:00:00

abstract：:Intelligent packaging can provide better preservation and advanced convenience for consumers. In this study, corn starch and polyvinyl alcohol (PVA) were used to produce films. Two easily accessible anthocyanin sources-purple sweet potato extracts (PSPE) and red cabbage extracts (RCE), were added respectively to evalu...

journal_title：International journal of biological macromolecules

authors： Zhang K,Huang TS,Yan H,Hu X,Ren T

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:Lipase is an enzyme that catalyzes the hydrolysis of lipids in watery and organic interactions they can catalyze synthetic reactions, involving inter esterification among triglycerides and alcohols to produce glycerin and fatty acids. The recovery of soluble lipase is not possible which makes this assay meth...

journal_title：International journal of biological macromolecules

authors： Atiroğlu V

更新日期：2020-02-15 00:00:00

abstract：:Starch nanoparticles (SNPs) have become one of the most interesting nanocarriers due to their relatively easy synthesis, biocompatibility, and biodegradability. However, the practical applications of SNPs are limited, as their aggregation reduce their functionality. Here, SNPs obtained by recrystallizing debranched wa...

journal_title：International journal of biological macromolecules

authors： Chang R,Lu H,Tian Y,Li H,Wang J,Jin Z

更新日期：2020-02-15 00:00:00

abstract：:N-acetylglucosaminidase produced from Lecanicillium lecanii on submerged culture displayed hydrolytic and transglycosylation activities. The highest specific activity for the enzyme was 1.87 U/mg after 120 h of culture. The chromatographic purification for a single protein fraction showed a molecular weight of 50.4 kD...

journal_title：International journal of biological macromolecules

authors： Rojas-Osnaya J,Rocha-Pino Z,Nájera H,González-Márquez H,Shirai K

更新日期：2020-02-15 00:00:00

abstract：:Lectins are proteins that have as one of their main characteristics recognizing and reversibly binding to carbohydrates. In this work, it was possible to purify and characterize a lectin from Parkia panurensis (Leguminosae family; Mimosoideae subfamily) seeds by a combination of the techniques: protein precipitation, ...

journal_title：International journal of biological macromolecules

authors： Cavada BS,Bari AU,Pinto-Junior VR,Lossio CF,Silva MTL,Souza LAG,Oliveira MV,Souza-Filho CHD,Correia SEG,Vital APMS,Lima LD,Osterne VJS,Nascimento KS

更新日期：2020-02-15 00:00:00

abstract：:The utilization from biomass feedstocks to fabricate the advanced nanomaterials has greatly attracted a great interest due to their low cost and sustainability. This work aimed to explore a simple way to prepare cellulose nanofibers using water-based approach via mechanical defibrillation. Cellulose fibers were first ...

journal_title：International journal of biological macromolecules

authors： Pakutsah K,Aht-Ong D

更新日期：2020-02-15 00:00:00

abstract：:To understand the contribution of granule inner portion to the pasting property of acetylated potato starch under the electric field and ultrasonic treatment, these starches were subjected to chemical surface gelatinization by 4.0 mol/L CaCl2 to obtain remaining granules with pasting time 0, 6, 12, 18, 24, 30 min, res...

journal_title：International journal of biological macromolecules

authors： Cao M,Gao Q

更新日期：2020-02-15 00:00:00

abstract：:Heat-moisture treatment (HMT) of starch is defined as a physical method to change its properties. Compared with maize and potato, starches from common buckwheat (Xinong9976 and Pingqiao2) were isolated and its morphology and physicochemical properties investigated by scanning electron microscope (SEM), X-ray diffracti...

journal_title：International journal of biological macromolecules

authors： Gao L,Xia M,Li Z,Wang M,Wang P,Yang P,Gao X,Gao J

更新日期：2020-02-15 00:00:00

abstract：:Angiogenesis is one of the most important processes in repair and regeneration of many tissues and organs. Blood vessel formation also play a major role in repair of dental tissue(s) after ailments like periodontitis. Here we report the preparation of chitosan/carboxymethyl cellulose/hydroxyapatite based hydrogels, lo...

journal_title：International journal of biological macromolecules

authors： Malik MH,Shahzadi L,Batool R,Safi SZ,Khan AS,Khan AF,Chaudhry AA,Rehman IU,Yar M

更新日期：2020-02-15 00:00:00

abstract：:A new green hydrogel has been synthesized by crosslinking lignosulfonate (L), sodium alginate (SA) and konjaku flour (KJ). We have optimized the ratio of the three synthesized polymers using an orthogonal design of experiments and characterized this hydrogel using SEM, BET and FTIR spectra. We have added the hydrogel ...

journal_title：International journal of biological macromolecules

authors： Song B,Liang H,Sun R,Peng P,Jiang Y,She D

更新日期：2020-02-01 00:00:00

abstract：:The present study investigates the purification, structure and in vitro antioxidant activities of a novel water soluble polysaccharide (LWSP) extracted from Linum usitatissimum L. seeds and evaluates the in vivo wound healing performance on CO2 laser fractional burn in a rat model. LWSP is a heteropolysaccharide that ...

journal_title：International journal of biological macromolecules

authors： Trabelsi I,Slima SB,Ktari N,Bardaa S,Elkaroui K,Abdeslam A,Ben Salah R

更新日期：2020-02-01 00:00:00

abstract：:To explore a valuable new enzyme method that effectively changes the molecular structure and absorption property of potato and sweet potato starch granules, the common combination of α-amylase (AA) and glucoamylase (GA), namely AA → GA (common method as contrast), the combination of glycosyltransferase (GT) and GA, na...

journal_title：International journal of biological macromolecules

authors： Guo L,Li J,Li H,Zhu Y,Cui B

更新日期：2020-02-01 00:00:00

abstract：:In this work, granular cold-water soluble waxy corn starch (N-GCWS) and granular cold-water soluble porous waxy corn starch (P-GCWS) were prepared by waxy corn starch (WS) treated with alcohol-alkali. Starch morphologies, crystal structures, turbidity, cold water viscosity, freeze-thaw stability and oil absorption cap...

journal_title：International journal of biological macromolecules

authors： Chen Y,Dai G,Gao Q

更新日期：2020-02-01 00:00:00

abstract：:A protein extract obtained from fig tree (Ficus carica) latex containing ficin activity was immobilized on glyoxyl agarose. Different biocatalyst loadings were used (3, 10, 30 and 85 mg/g). When casein was used as substrate, the expressed activities were 60%, 58%, 41% and 14%, respectively, very likely due to casein d...

journal_title：International journal of biological macromolecules

authors： Siar EH,Morellon-Sterling R,Zidoune MN,Fernandez-Lafuente R

更新日期：2020-02-01 00:00:00

abstract：:Dermatophagoides farinae is a major exogenous allergen. Its ability to tolerate adverse external temperatures makes it responsible for widespread occurrence of allergies. Heat shock protein (HSP), a recognized temperature stress response gene, but its role in D. farinae remained unclear. Here, we performed a comprehen...

journal_title：International journal of biological macromolecules

authors： Niu D,Zhao Y,Gong X,Yang R,Hu L,Zhang W

更新日期：2020-02-01 00:00:00

abstract：:The structural modification of polysaccharides directly affects their physicochemical properties and applications. Dextran, a chained polysaccharide, consists of multiple d-glucose molecules with repetitive structures. In this study, the physicochemical properties of oxidized dextran (DO) at different concentrations o...

journal_title：International journal of biological macromolecules

authors： Wu H,Shang-Guan DC,Lu QM,Hu XQ,Yang JW,Zhang HB

更新日期：2020-02-01 00:00:00

abstract：:The current study involves development of novel tamarind seed gum - alginate complex microspheres for sustained release of dalfampridine by using Central Composite design in combination with response surface methodology. Polymer ratio (A), agitation speed (B) and concentration of CaCl2 (C) were selected as independent...

journal_title：International journal of biological macromolecules

authors： Doniparthi J,B JJ

更新日期：2020-02-01 00:00:00

abstract：:The present study aimed to evaluate the antidepressant-like effect of a polysaccharide (OP), which is isolated from okra (Abelmoschus esculentus (L) Moench), in CUMS-induced mice and its possible mechanisms. OPT, FST and TST were employed to examine the anxiety and depressive behavior in CUMS-induced mice and fecal mi...

journal_title：International journal of biological macromolecules

authors： Yan T,Nian T,Liao Z,Xiao F,Wu B,Bi K,He B,Jia Y

更新日期：2020-02-01 00:00:00

abstract：:This paper introduces a cheap simple MWCNTs@paper biosensor for the detection of CA19-9, which is a biomarker of pancreatic cancer. By adding the CA19-9 antibody to the surface of MWCNTs which are deposited on the microporous filter paper, the correlation between the concentration of CA19-9 and resistance of biosensor...

journal_title：International journal of biological macromolecules

authors： Jin W,Zhang R,Dong C,Jiang T,Tian Y,Yang Q,Yi W,Hou J

更新日期：2020-02-01 00:00:00

abstract：:The objectives of this study were to investigate and compare the structural and physicochemical properties of native ginger starch (NGS) and ginger resistant starch (GRS). NGS had oblate and compact granules, whereas GRS exhibited fissures. Compared to GRS, NGS had a narrower molar mass distribution and a higher molec...

journal_title：International journal of biological macromolecules

authors： Li X,Chen W,Chang Q,Zhang Y,Zheng B,Zeng H

更新日期：2020-02-01 00:00:00

abstract：:Snail mucus is an attractive natural substance, which is increasingly used in cosmetic creams and syrups thanks to its emollient, moisturizing, protective and reparative properties. The aim of the present study was to explore the physicochemical properties of chitosan-based films added with snail mucus extracted from ...

journal_title：International journal of biological macromolecules

authors： Di Filippo MF,Panzavolta S,Albertini B,Bonvicini F,Gentilomi GA,Orlacchio R,Passerini N,Bigi A,Dolci LS

更新日期：2020-01-15 00:00:00

abstract：:The heat shock 70/90 organizing protein is one of the stress-induced proteins and has extensively been studied in mammals. It mediates the interaction of Hsp70 and Hsp 90 as cochaperone and also implicated in infection-related processes. However, the biological role of heat shock 70/90 organizing protein in silkworm r...

journal_title：International journal of biological macromolecules

authors： Kausar S,Abbas MN,Yang L,Cui H

更新日期：2020-01-15 00:00:00

abstract：:Herein, positively surface-charged silver nanoparticles (AgNPs) capped with trimethylchitosan nitrate (TMCN) were synthesized using an environmentally friendly method. Nano-sized TMCN-AgNPs (~80 nm) with high zeta potential (>30 mV) provide sufficient static repulsion to stabilize colloid AgNPs in aqueous solutions wi...

journal_title：International journal of biological macromolecules

authors： Wang SH,Chen CC,Lee CH,Chen XA,Chang TY,Cheng YC,Young JJ,Lu JJ

更新日期：2020-01-15 00:00:00

abstract：:An arabinogalactan (ICPA) was isolated from the water extract of Ixeris chinensis (Thunb.) Nakai. ICPA was mainly composed of galactose and arabinose with minor amount of glucose. The molecular weight of ICPA was 58.1 kDa. Structural analysis by methylation and NMR spectroscopy indicated that ICPA contained α-D-Glcp(1...

journal_title：International journal of biological macromolecules

authors： Li H,Xie W,Qiao X,Cui H,Yang X,Xue C

更新日期：2020-01-15 00:00:00

abstract：:The present study aimed at developing edible composite films from pearl millet starch (PMS) and carrageenan gum (CG) blends. Central composite rotatable design of response surface methodology was used to optimize concentrations of PMS (2-5%), carrageenan (1-3.5%) and glycerol (15-35%) for the development of composite ...

journal_title：International journal of biological macromolecules

authors： Sandhu KS,Sharma L,Kaur M,Kaur R

更新日期：2020-01-15 00:00:00

abstract：:Marine species have gained significant attention as potential source for a broad spectrum of bioactive proteins. Fish phospholipases A2 (PLA2) have attracted renewed interest due to their excellent properties in lipid digestion. Herein, we report for the first time the catalytic properties of two intestinal secreted P...

journal_title：International journal of biological macromolecules

authors： Smichi N,Parsiegla G,Achouri N,Zarai Z,Abousalham A,Fendri A

更新日期：2020-01-15 00:00:00

abstract：:For the first time, the effect of two novel designed pentapeptides on amyloid growth of human insulin using combined biophysical, microscopic, cell viability and computational approaches. Collective experimental data from ThT, ANS, and TEM demonstrate that in spite of having contrasting features, both peptides can eff...

journal_title：International journal of biological macromolecules

authors： Siddiqi MK,Majid N,Alam P,Malik S,Alam A,Rajan S,Ajmal MR,Khan RH

更新日期：2020-01-15 00:00:00

abstract：:Due to the incongruence of morphology-based hypotheses and scarcity of molecular data, validity of the order Tetraonchidea remains contentious. The only complete mitogenome currently available for the entire order is that of Paratetraonchoides inermis (Tetraonchoididae). To study the phylogeny of Tetraonchidea from mi...

journal_title：International journal of biological macromolecules

authors： Zhang D,Li WX,Zou H,Wu SG,Li M,Jakovlić I,Zhang J,Chen R,Wang GT

更新日期：2020-01-15 00:00:00

abstract：:In this study, the structure of inulin was chemically modified by Schiff bases in order to improve its biological activity. A total of 6 kinds of inulin derivatives were synthesized according to aza-Wittig reaction. Their structures were confirmed by FTIR, 1H NMR, and 13C NMR spectroscopy. The antioxidant activity of ...

journal_title：International journal of biological macromolecules

authors： Chen Y,Mi Y,Li Q,Dong F,Guo Z

更新日期：2020-01-15 00:00:00

abstract：:The main objective of this work was to study the possibility of using polysaccharides and lignin as a coating material for water-soluble triple superphosphate (TSP) granular fertilizers. In this study, composites based on three polysaccharides (sodium alginate (alginic acid sodium salt): AL, kappa-carrageenan: CR and ...

journal_title：International journal of biological macromolecules

authors： Fertahi S,Bertrand I,Ilsouk M,Oukarroum A,Amjoud M,Zeroual Y,Barakat A

更新日期：2020-01-15 00:00:00

abstract：:Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes. However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating enzymatic activity and their medical applications. To overcome these challenges, it is necessary to explore how enzymes attach to nanomateria...

journal_title：International journal of biological macromolecules

authors： Sharifi M,Sohrabi MJ,Hosseinali SH,Hasan A,Kani PH,Talaei AJ,Karim AY,Nanakali NMQ,Salihi A,Aziz FM,Yan B,Khan RH,Saboury AA,Falahati M

更新日期：2020-01-15 00:00:00

abstract：:Calcium alginate hydrogel dressing is an excellent hydrogel dressing because of its excellent absorption characteristics and tear-free pain. However, its application is limited by its poor mechanical properties and non-bacterial properties. Here, we reported a new biomimetic hydrogel dressing with good mechanical prop...

journal_title：International journal of biological macromolecules

authors： Zhang M,Chen S,Zhong L,Wang B,Wang H,Hong F

更新日期：2020-01-15 00:00:00

abstract：:The present study focused on production, optimization and characterization of exopolysaccharide (EPS) from Weissella confusa MD1. The purified EPS MD1 was also evaluated for in vitro biological activities. The maximum yield of EPS (10.07 ± 0.32 g/L) was obtained with optimized culture conditions of 35 °C at pH 6.5 for...

journal_title：International journal of biological macromolecules

authors： Lakra AK,Domdi L,Tilwani YM,Arul V

更新日期：2020-01-15 00:00:00